Chemical Analysis: Total Organic Carbon (TOC), O.I. Device Extraction (GLP)

Total organic carbon is the bulk measure of how much organic material comes off your device into water. It does not identify anything — it quantifies the total, which makes it a fast screen and a check that an extraction went far enough.

SKU: GRK-2018
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When this test applies

As a screening and verification measure inside a chemical characterisation programme. TOC gives one number for the total organic burden in an aqueous extract, which makes it useful early — before committing to the full identification work — and useful again at the end, as a check that successive extractions have driven the recoverable organics down.

When to run it

Early, as an inexpensive read on whether there is much to find, or alongside a full profile as a mass-balance check. It is not a substitute for the identification arms: if TOC comes back high, the next question is what is it, and only VOC, SVOC and NVOC analysis answers that.

What the result gives you

A quantified total organic carbon value for the aqueous extract, with the extraction conditions documented. Read against a control and against successive extractions, it tells you the size of the organic burden and whether it is falling.

What it does not settle

TOC identifies nothing. A single number cannot be assessed against a tolerable exposure, because tolerable exposure is per constituent — so TOC never closes a toxicological question on its own. It is also aqueous only: organics that water does not recover are invisible to it, which is why the IPA and hexane arms of the profile exist.

Method

Device extraction per the O.I. protocol, with the aqueous extract analysed for total organic carbon by TOC analyser.

Where it runs

This analysis is subcontracted to an ISO/IEC 17025 accredited, GLP certified laboratory, and the report is issued under Groenakker cover, in Groenakker’s report template or in your document template on request at no extra cost.

Usually ordered alongside

The identification arms of the profile — VOC, SVOC and NVOC across water, IPA and hexane — and an ISO 10993-17 assessment to interpret them. Non-volatile residue is the gravimetric counterpart to this measurement.

Products specifications
SubcontractedYes
EndpointChemical Characterisation
Method detail
Test systemAnalytical - total organic carbon analyser
MethodTotal organic carbon (TOC), O.I. device extraction
ExtractionDevice extraction per the O.I. protocol; aqueous extract analysed for total organic carbon.
Acceptance criteriaTOC is reported as mg C per device or per mL and read against the threshold applied in the accompanying chemical or toxicological evaluation. Note: TOC is a screening measure, not a pass/fail endpoint in its own right.
DeliverableGLP-compliant final report with raw data, issued in Groenakker’s report template or in your document template on request at no extra cost, under Groenakker’s ISO 13485:2016 certified quality system.
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